Fig. 5
From: Reversibility of Vasalgel™ male contraceptive in a rabbit model
Rabbit vas deferens examined after device reversal procedure. a Longitudinal section (100X magnification) of vas deferens, containing residual material appearing as homogenous luminal substance. The ★ depicts a layer of granulomatous inflammation which replaces the mucosal epithelial cells. Muscularis (M), vas deferens lumen (L). Bar = 100 μm. b Cross section (100X magnification) of vas deferens containing fragmented residual material. Muscularis (M), vas deferens lumen (L). Bar = 100 μm. c Longitudinal section (200X magnification) of vas deferens. Fragmented material is present in the lumen. The mucosal epithelium is attenuated in this photomicrograph (arrow). Muscularis (M), vas deferens lumen (L). Bar = 50 μm. d Longitudinal section (100X magnification) of vas deferens. The lumen is empty and tall columnar epithelium is present. Muscularis (M), vas deferens lumen (L). Bar = 100 μm. e Additional longitudinal section (200X magnification) of vas deferens. Clumps of spermatozoa are present in this image (arrows). Muscularis (M), vas deferens lumen (L). Bar = 50 μm. f Extraluminal adventital material with associated granulomatous inflammation (200X magnification). Arrows depict a multinucleated giant cells adjacent eosinophilic to amphophilic material in the interstitium. Bar = 50 μm